Emergency services were called at 11:05am after reports that a heavy vehicle towing a digger had collided with a car on the Fernhill Road in Rutherglen.
Five cars and a bus were also involved in the incident.
-- Advertisement --
The male driver of the car was pronounced dead at the scene. The driver of the agricultural vehicle was taken to hospital where his condition is described as serious.
Sgt Alison McAuley of Police Scotland said: "An extensive recovery operation, which is expected to last for several more hours, is currently underway and Fernhill Road is closed with local diversions in place.
"I would appeal to anyone who witnessed what happened to contact officers at the Divisional Road Policing Unit based at Motherwell on 101."
(LM)
